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What Is an Aortic Dissection?

The condition that killed Senator Lindsey Graham is deadly, sudden and difficult to treat β€” β€œlike a knife to the heart,” one expert said.

On Saturday night, Senator Lindsey Graham, Republican of South Carolina, died of an aortic dissection β€” a rip in the aorta, the main artery carrying blood from the heart to the rest of the body.

Such a tear is a medical emergency. Fifty percent of patients make it to the hospital, and about half survive, said Dr. Michael Mack, a heart surgeon who is chair of the research institute Baylor Scott & White Health in Dallas.

Dr. Mack added that an aortic dissection is the first thing that comes to mind when a patient who is feeling well dies suddenly.

The wall of the aorta has three layers, said Dr. Kendra J. Grubb, a heart surgeon formerly at Emory University and now at Medtronic, the medical device company. A dissection occurs in the inner layer, allowing blood to pour in between the layers of the tubelike vessel.

It’s most likely caused by an underlying aortic aneurysm β€” a bubble in the vessel, similar to what can occur in old bicycle tubes. Aortic aneurysms can be caused by high blood pressure, atherosclerosis or some rare underlying genetic conditions, like bicuspid aortic valves.

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